Subthalamic neuronal responses to cortical stimulation.
Identifieur interne : 000C03 ( Main/Exploration ); précédent : 000C02; suivant : 000C04Subthalamic neuronal responses to cortical stimulation.
Auteurs : Marcus L F. Janssen [Pays-Bas] ; Daphne G M. Zwartjes ; Yasin Temel ; Vivianne Van Kranen-Mastenbroek ; Annelien Duits ; Lo J. Bour ; Peter H. Veltink ; Tjitske Heida ; Veerle Visser-VandewalleSource :
- Movement disorders : official journal of the Movement Disorder Society [ 1531-8257 ] ; 2012.
English descriptors
- KwdEn :
- MESH :
- methods : Deep Brain Stimulation.
- pathology : Subthalamic Nucleus.
- physiology : Action Potentials, Cerebral Cortex, Evoked Potentials, Motor, Neurons.
- therapy : Parkinson Disease.
- Aged, Female, Humans, Male, Middle Aged.
Abstract
Deep brain stimulation of the subthalamic nucleus alleviates motor symptoms in Parkinson's disease patients. However, some patients suffer from cognitive and emotional changes. These side effects are most likely caused by current spread to the cognitive and limbic territories in the subthalamic nucleus. The aim of this study was to identify the motor part of the subthalamic nucleus to reduce stimulation-induced behavioral side effects, by using motor cortex stimulation.
DOI: 10.1002/mds.24053
PubMed: 22213381
Affiliations:
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Le document en format XML
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<sourceDesc><biblStruct><analytic><title xml:lang="en">Subthalamic neuronal responses to cortical stimulation.</title>
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<author><name sortKey="Duits, Annelien" sort="Duits, Annelien" uniqKey="Duits A" first="Annelien" last="Duits">Annelien Duits</name>
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<author><name sortKey="Visser Vandewalle, Veerle" sort="Visser Vandewalle, Veerle" uniqKey="Visser Vandewalle V" first="Veerle" last="Visser-Vandewalle">Veerle Visser-Vandewalle</name>
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<term>Evoked Potentials, Motor (physiology)</term>
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<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Neurons (physiology)</term>
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<front><div type="abstract" xml:lang="en">Deep brain stimulation of the subthalamic nucleus alleviates motor symptoms in Parkinson's disease patients. However, some patients suffer from cognitive and emotional changes. These side effects are most likely caused by current spread to the cognitive and limbic territories in the subthalamic nucleus. The aim of this study was to identify the motor part of the subthalamic nucleus to reduce stimulation-induced behavioral side effects, by using motor cortex stimulation.</div>
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<name sortKey="Heida, Tjitske" sort="Heida, Tjitske" uniqKey="Heida T" first="Tjitske" last="Heida">Tjitske Heida</name>
<name sortKey="Temel, Yasin" sort="Temel, Yasin" uniqKey="Temel Y" first="Yasin" last="Temel">Yasin Temel</name>
<name sortKey="Van Kranen Mastenbroek, Vivianne" sort="Van Kranen Mastenbroek, Vivianne" uniqKey="Van Kranen Mastenbroek V" first="Vivianne" last="Van Kranen-Mastenbroek">Vivianne Van Kranen-Mastenbroek</name>
<name sortKey="Veltink, Peter H" sort="Veltink, Peter H" uniqKey="Veltink P" first="Peter H" last="Veltink">Peter H. Veltink</name>
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<name sortKey="Zwartjes, Daphne G M" sort="Zwartjes, Daphne G M" uniqKey="Zwartjes D" first="Daphne G M" last="Zwartjes">Daphne G M. Zwartjes</name>
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<country name="Pays-Bas"><noRegion><name sortKey="Janssen, Marcus L F" sort="Janssen, Marcus L F" uniqKey="Janssen M" first="Marcus L F" last="Janssen">Marcus L F. Janssen</name>
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